Preterm Neuroimaging and School-Age Cognitive Outcomes

PRETERM NEUROIMAGING The prediction of neurodevelopmental outcomes among infants born at <28 weeks' gestational age is challenging and inexact. This prospective study assessed the usefulness of near-term neuroimaging in predicting the development of poor neurodevelopmental outcomes among these infants and found that at school age, there was a consistent association between near-term adverse cranial ultrasound findings (35-42 weeks' gestational age) and cognitive impairment compared to early CUS (4-14 days of age) or MRI. Thus, near-term cranial ultrasound may be a useful predictor of neurodevelopmental outcome in infants born at <28 weeks' gestational age.

Does umbilical cord milking result in higher measures of systemic blood flow in preterm infants?

UMBILICAL CORD MILKING While delayed cord clamping is recommended for all preterm neonates, whether umbilical cord milking confers the same benefits is unkown. This randomized controlled trial compared delayed cord clamping and cord milking among preterm infants delivered by cesarean section. While underpowered to detect statistically significant differences in IVH, the trial’s findings suggest that umbilical cord milking results in greater placental transfusion and possible improved organ perfusion. Importantly, long-term follow up is necessary to further assess outcomes following use of these methodologies.