December 2015

Does umbilical cord milking result in higher measures of systemic blood flow in preterm infants?

UMBILICAL CORD MILKING While delayed cord clamping is recommended for all preterm neonates, whether umbilical cord milking confers the same benefits is unkown. This randomized controlled trial compared delayed cord clamping and cord milking among preterm infants delivered by cesarean section. While underpowered to detect statistically significant differences in IVH, the trial’s findings suggest that umbilical cord milking results in greater placental transfusion and possible improved organ perfusion. Importantly, long-term follow up is necessary to further assess outcomes following use of these methodologies.

Does single mega-dose vitamin A in the early neonatal period reduce mortality during infancy in low- and middle-income countries?

Vitamin A Deficiency Maternal Vitamin A deficiency is common in low- and medium-resource settings and is associated with increased infant mortality. This randomized controlled trial assessed whether oral Vitamin A supplementation delivered to neonates within 72 hours of birth could reduce mortality in the first 6 months of age. Although supplementation resulted in short-term improvements in Vitamin A deficiency, no significant difference in mortality was found. While further analysis is necessary, neonatal Vitamin A supplementation is not effective in preventing infant mortality.