The latest review of the RCT on hypercapnia has generated a lot of discussion on Twitter.
The main issue discussed is the disappointment in stopping the trial prematurely, leaving the principal question still not resolved. See some example tweets below.
And… a friendly reminder: our comment field is now open for anyone to comment on. We validate the first comment from everyone but after that (given you use the same email address) all comments are directly published.
.@EBNEO shame the hypernapia study finished early… Underpowered for outcome? Another studies happening? #foamneo
— Jonathan Davis (@jonathan_davis3) November 2, 2015
I am increasingly baffled by reasons for stopping RCTs, that then go on to conclude study underpower.@jonathan_davis3 @johansson247 @EBNEO
— SlowRoastPork (@slowroastpork) November 3, 2015
Great to see a randomised trial addressing such a difficult and important question, such a shame it stopped early. https://t.co/50OoK9fFnc
— Chris Gale (@DrCGale) November 3, 2015
@KarenLuyt @EBNEO @jonathan_davis3 – isn't cerebral autoreg pretty narrow in babies anyway? How to RCT… center/cluster design?
— Josh Attridge (@tree95) November 5, 2015
