June 2015

Cord stripping in preterm neonates

CORD STRIPPING Delayed cord clamping has been associated with improved neonatal outcomes. This randomized controlled trial studied whether cord stripping in additon to delayed cord clamping improves outcomes in preterm neonates when compared to delayed cord clamping alone. Though trends suggested a possible benefit when combining cord stripping with delayed cord clamping, there were no significant differences found between either strategy.

Longer treatment for symptomatic congenital cytomegalovirus infection may have only modest long-term benefits.

VALGANCICLOVIR The long-term audiologic benefits of ganciclovir treatment for CMV infection are unclear. This randomized controlled trial evaluated the effectiveness of 6 week or 6 month valganciclovir therapy in improving audiologic outcomes. Although short-term outcomes were not different between groups, 6 month-treatment was associated with a slight improvement in hearing and neurodevelopmental outcome at 12 and 24 months. Thus, extended valganciclovir treatment may be appropriate for CMV infection.

Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants

FORMULA Nutrition for extremely preterm infants is critical to growth and development. This randomized controlled trial examined the short-term outcomes of feeding these infants on an exclusively bovine or exclusively human milk diet, and found that an exclusive fortified human milk diet resulted in improved short-term outcomes, including a reduction in NEC and days on PN. Long-term follow up is essential to the conclusion of this trial that human milk PN is safe for extremely preterm infants.